Higher muscle mass associated with lower mortality risk in people with heart disease

ScienceDaily.com
CutDate:  April 22, 2016
Source:  University of California, Los Angeles (UCLA), Health Sciences
Summary:
Cardiovascular disease patients who have high muscle mass and low fat mass have a lower mortality risk than those with other body compositions, researchers have found. The findings also suggest that regardless of a person’s level of fat mass, a higher level of muscle mass helps reduce the risk of death.

Full Article

Researchers from the David Geffen School of Medicine at UCLA found that cardiovascular disease patients who have high muscle mass and low fat mass have a lower mortality risk than those with other body compositions. The findings also suggest that regardless of a person’s level of fat mass, a higher level of muscle mass helps reduce the risk of death.

This findings indicate the importance of assessing body composition as a way to help predict cardiovascular and total mortality in people with cardiovascular disease.

Background

In previous studies on the relationship between body composition and mortality, the researchers used a simpler clinical measure of body composition called the bio electrical impedance scale. They noted a possible protective effect of muscle mass on both mortality and metabolism in healthy people. The new study extends the findings from the earlier research using dual X-ray absorptiometry, a more rigorous method of measuring body composition.

The researchers examined data from the National Health and Nutrition Examination Survey, 1999 to 2004, of 6,451 participants who had prevalent cardiovascular disease. Each subject was categorized into one of four groups:

  • low muscle/low fat mass
  • low muscle/high fat mass
  • high muscle/low fat mass
  • high muscle/high fat mass

Those with high muscle mass and low fat mass had the lowest risk of cardiovascular and total mortality.

Impact

Because people with higher muscle mass were more likely to have a high body mass index, the findings could explain the “obesity paradox,” which holds that people with a higher BMI have lower mortality levels.

The findings also highlight the importance of maintaining muscle mass, rather than focusing on weight loss, in order to prolong life, even in people who have a higher cardiovascular risk. The authors suggest that clinicians encourage their patients to participate in resistance exercises as a part of healthy lifestyle changes, rather than focusing primarily on, and monitoring, weight loss.

Authors

Dr. Preethi Srikanthan, associate clinical professor of medicine in the division of endocrinology at the David Geffen School of Medicine, is the study’s primary investigator. The study’s co-authors are Dr. Tamara Horwich, health sciences clinical professor of medicine, division of cardiology, and Dr. Chi-hong Tseng, adjunct associate professor of medicine in the division of general internal medicine and health services research.

The study was published in the American Journal of Cardiology.


Story Source:

The above post is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences. The original item was written by Enrique Rivero. Note: Materials may be edited for content and length.


Journal Reference:

  1. Preethi Srikanthan, Tamara B. Horwich, Chi Hong Tseng. Relation of Muscle Mass and Fat Mass to Cardiovascular Disease Mortality. The American Journal of Cardiology, 2016; 117 (8): 1355 DOI: 10.1016/j.amjcard.2016.01.033
Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s